Can people stop saying stuff like "I wish I was X" or "I wish that would happen to me"? I'm not sure how desensitized e6 is to this stuff but it's annoying and wierd

The people who make those comments generally don't use the forums. Just report the comments when you see them.

https://e621.net/wiki/show/e621:rules

Creepy Comments
Suggested Suspension Length: 3 days
This category includes:

• Creating forum posts, threads, or comments that cause an unpleasant feeling of fear or unease, or are sexually inappropriate

This is intended to ensure that users do not express their personal fetishes/desires publicly. Users have the right, within realistic expectations, to browse comfortably without unneeded or unnecessary commentary of those who wish to express their desires.

As long as the comment is newer than one month old, you can report it for this reason.