When going into Blacklist I'm constantly tempted to Blacklist. "Human" Because I hate seeing Human x Pony pictures. However sometimes I do wander off into other areas of the site at which point I don't mind seeing pics with humans in them.

Is there a way to add 2 tags to Blacklist that will blacklist a picture only if both tags are in it?

For example: Human, MLP

Is there a way to fix up the Blacklist so that when both tags appear in a picture, that picture is blacklisted. But if they appear separate, the picture is not blacklisted. (Because I still want to see humans, just. Not with ponies)

Put tags on the same line separated by spaces. That should hide an image only if it has all the tags of that line.

So, putting "human mlp" in your blacklist on the same line will hide every image whitch has both of those tags.

Read help:blacklist for more.

Here's a tip: many don't see the blacklist as this, look at it as a search box, where the tags you're searching for will return the posts you don't want to see. This has two advantages, 1) no tag limit per search and 2) many searches at once.

Now, what you ask for, your "search" should be "human pony my_little_pony" (the exact stuff you don't want to see). So just add that to your blacklist and you should be good to go