Criss-Crossbreeding is a comic starring Faithry, the sadistic scientist who runs the sexual experiment lab on Faithry Island. In this particular comic, the central test subject is a male donkey named Hinny who is forced to have sex with, and impregnate, a variety of Faithry's female test subjects. First he is forced to take part in bestiality, knocking up a feral unicorn, deer, and goat.
Next, the situation is reversed, and Hinny is himself transformed into a feral donkey and forced to impregnate anthros Olonia, Veroa, and Zenaida.
Finally, Hinny's role in all the crossbreeding experiments done, he is transformed back into an anthro and strapped into an empty fountain, where an electrostimulation apparatus forces him to ejaculate every hour on the hour as a form of clock.