I think Deathclaws and Super Mutants were nerfed in Fallout 4, because I don't have much trouble taking them down at level 18 with a combat rifle (who's damage is 49 at the moment). Deathclaws and Super Mutants were extremely dangerous in New Vegas.
Responses
In response to blip #66630
@Chameloshi: Lots of things were nerfed in FO4, like free will and its own existence in canon (thanks to songs that were never composed).
In response to blip #66630
@Chameloshi: totally, I got attacked by a dethclaw in fallout3 and had to take every med I had to barley survive.