I recently flagged post #1148023 and post #1148022 for being inferior to post #3897885 and post #3897810 respectively (they are almost 2/3 times bigger), but the much smaller Tumblr samples ended up deleted instead because the Twitter versions had some compression artifacts on account of them being from Twitter. I was told by the Janitor who deleted them that "[e621 does] not go by resolution" when choosing which version to keep, but this is directly at odds with the flag page which lists being larger as a reason to keep one version over another.
When I asked, the same Janitor also disclosed that they might keep even a 500x500 PNG from Pixiv over a 3000x3000 Twitter JPG, which is just absurd. Being over 60% bigger should already be enough to offset such compression, but apparently even if those images were 500% bigger they still wouldn't have made the cut. I could understand if the image was only, say, 10% bigger, or if the compression was akin to some deep-fried meme, but completely ordinary run-of-the-mill Twitter compression isn't nearly enough justification to ignore such a substantial size increase.
The flag for deletion wiki page and the "Duplicate or inferior version of another post" option on the New Flag page need to go into more detail in regards to what actually constitutes as an inferior version, the staff needs to be consistent with said rules when selecting which post to keep, and substantially larger images should not be thrown out for mere Twitter compression.