Titled "50 Cartoon Crushes: Cleo (Heathcliff/Cats & Co., 1984)"
From the artist:

Crush Class: C (childhood)

Probably my 1st legit 'furry crush', this blonde kitty alternated between snarky & flirty, depending on mood (or writer). A curious amount of screen time was spent on Cleo & Riff Raff's love life for a kids' cartoon.