I can relate to all of this.

In terms of Derpy's pain, I can relate. When people are too busy (or "distracted" in this case) to listen to what you have to say even though it's actually really important and in-turn you are left to deal with a very significant problem by yourself, it hurts. It really does. Especially in Derpy's case where people tend to not take her as seriously as they may others due to her personality/demeanor.

And the fact that Firefly is crying as if it's her problem really gets to me too. I feel like her regret is warranted, but I also kind of feel like if she had just listened, it would not have hurt everyone as much. (Which is true in a sense) And that's why she hurts. She feels like everyone else's pain is her fault.

As a person in both of those places in my own life I can relate to that pain. Both Derpy's and Firefly's.

For me this entire emotional situation can go two ways:

On one hand I kind of feel that while Firefly does have regret, how is anyone supposed to sympathize with her when in a way she's the one at fault for her own regret?

I mean, she had one job: Listen to Derpy and help her. Why? Well because she was the only friend Derpy actually trusted enough to do listen to her and help her. But instead of doing what she needed to she decided to get caught up in her own emotions with Dash and the "school team" thing. So now all of them (derpy, dash, and firefly) have to suffer the consequences in their own way, yet Derpy still takes the greatest fall in terms of the total amount of emotional and physical pain to have to suffer through.

But yet on the other hand I am not inclined to make Firefly the enemy here either. Besides, can you really blame it all on her?

I mean she has so much on her plate as far as her life and offering what she can in the lives of others that this single neglectful action towards derpy could have easily been overlooked by anyone else in her place. And if she had paid more attention to derpy, then maybe one of her other priorities may have suffered just as much or more from the same amount of neglect, even if that priority happened to be her own well-being.

*sigh*

But I don't know. Certain things in this entire comic gets to me emotionally. This is just the first time I've actually sat down just to say anything about it extensively.