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Experiment 627 ("six-two-seven") is one of Dr. Jumba Jookiba's genetic experiments in the Lilo & Stitch franchise. A red furred koala-like alien creature, he is Dr. Jumba's first experiment created on Earth and his most powerful experiment ever, having much improved versions of his immediate predecessor Stitch's abilities (without any of his weaknesses) plus the abilities of at least twenty other experiments. 627 is designed to be so evil that he cannot be turned good. He was never rehabilitated by either Lilo or Stitch, and thus he wasn't named. The only word he could say was "Evil!", which led to the fans nicknaming him "Evile", although his vocabulary was greatly expanded in the Stitch! anime. His defining trait, besides being evil, is his twisted sense of humor that causes him to laugh a lot. Ironically for him, his heavy laughter is also his only known weakness; he becomes cataplectic and will collapse if he laughs too much.

627 is taller than his immediate predecessor, has six arms, four of which are retractable (and when they are extended, his torso appears muscular with an athletic build); has a cone-shaped head (and he can grow a second one), four retractable spines on his back, ears with symmetrical notches, tan countershading, a purple nose, and his red fur has a bit of an orange tint to it.

In the franchise, 627 has only appeared in one episode of Lilo & Stitch: The Series (plus a small cameo in another episode), one episode of the Stitch! anime, and in an animated short parodying High School Musical. Despite this, he has made appearances in Tokyo Disneyland and Disneyland Paris as a costumed character.