Examples of what this includes:

• Asgore Dreemurr × Toriel — In both Undertale and Deltarune, Asgore and Toriel were at one point married and had a son, Asriel Dreemurr, but have since divorced.
• Bonbon (MLP) × Lyra Heartstrings (MLP) — While these two have been a long time fanon couple, LyraBon was canonized in the final season of their series with a marriage proposal and wedding.
• Donald Duck × Daisy Duck — The character of Daisy Duck was created as a love interest for Donald Duck and has since been depicted romantically for over eighty years of Disney media.
• Nicole Watterson × Richard Watterson — These two have been married for the entirety of The Amazing World of Gumball's run.
• Sally Acorn × Sonic the Hedgehog — These two have been depicted romantically in Sonic SatAm and its spinoff comic series, in which they eventually married and had two children.

Examples of what are not included:

• Bea Santillo × Mae Borowski — Creator Scott Benson confirmed Bea as straight, meaning she would not pursue a relationship with Mae, who is just a friend.
• Felicity Parham × Richard Watterson — Felicity hates Richard's wife and their family; the only romantic context ever seen between these characters in The Amazing World of Gumball was a non-serious instance in "The Shippening", an episode parodying shipping culture.
• Jar Jar Binks × Lop (Star Wars Visions) — These characters have never met in any Star Wars media and have no knowledge of the other, let alone develop any feelings.
• Judy Hopps × Nick Wilde — The WildeHopps ship is the predominant Zootopia ship, even teased by co-director Rich More and encouraged by Nick's voice actor Jason Bateman, but Judy and Nick have not been outright said to date by any official media or creator statements.
• Mordecai (Regular Show) × Twilight Sparkle (MLP) — Mordetwi is a crackship between two characters that from copyrights of completely different ownership what would not feasibly allow an official crossover.

Below is a semi-comprehensive list of canon couples, sorted by copyright alphabetically. Please add to this with discretion to what is canonical. Just because your favorite fanon ship doesn't go here doesn't mean it isn't good; it just isn't canon.